Serotonergics

1-(1-Naphthyl)piperazine·HCl
A mixed modulator of serotonin 5-HT receptors. Demonstrates agonism of the 5-HT_1A receptors and antagonism of the 5-HT_2A/2C receptors.
カタログ # CAS Number Molecular Formula Unit
sc-201139 57536-86-4 14H₁₆N₂ ·HCl 20 mg/100 mg
1-Methylpsilocin
Potent and selective 5-HT2C agonist (IC₅₀ values are 12 and 633 nM for 5-HT2C and 5-HT2A receptors respectively). Displays high affinity for the 5-HT2B receptor (K_i = 38 nM) but acts as an inverse agonist. Active in vivo; inhibits scratching in a mouse model of OCD.
カタログ # CAS Number Molecular Formula Unit
sc-203764 1465-16-3 C₁₃H₁₈N₂O 10 mg/50 mg
1-Phenylbiguanide
カタログ # CAS Number Molecular Formula Unit
sc-222728 102-02-3 C₈H₁₁N₅ 25 g
1-Phenylbiguanide hydrochloride
5-HT3 receptor agonist.
カタログ # CAS Number Molecular Formula Unit
sc-203455 55-57-2 C₈H₁₁N₅.HCl 100 mg
2-[1-(4-Piperonyl)piperazinyl]benzothiazole
5-HT4 serotonin receptor agonist with moderate activity as a 5-HT3 serotonin receptor antagonist.
カタログ # CAS Number Molecular Formula Unit
sc-203767 N/A C₁₉H₁₉N₃O₂S 5 mg
2-Methylserotonin·HCl
A serotonin 5-HT₃ agonist shown to have low binding activity for 5-HT1A, 5-HT1B, 5-HT1C, and 5-HT2 binding sites.
カタログ # CAS Number Molecular Formula Unit
sc-201136 78263-90-8 C₁₁H₁₄N₂O•HCl•xH₂O 10 mg/50 mg
3-AQC
A competitive 5-HT3 antagonist, almost 100 times more potent than tropisetron, but with widely differing activity in various tissues.
カタログ # CAS Number Molecular Formula Unit
sc-203776 N/A C₁₆H₁₇N₅ ·C₄H₄O₄ 5 mg/25 mg
3-Oxo Citalopram
An intermediate of Citalopram and a potent and selective inhibitor of the 5-hydroxytryptamine transporter (serotonin).
カタログ # CAS Number Molecular Formula Unit
sc-209668 372941-54-3 C₂₀H₁₉FN₂O₂ 1 mg
4-[3-(Benzotriazol-1-yl)propyl]-1-(2-methoxyphenyl)piperazine oxalate
Strong pre- and postsynaptic 5-HT1A receptor antagonist.
カタログ # CAS Number Molecular Formula Unit
sc-220919 N/A C₂₂H₂₇N₅O₅ 5 mg
4F 4PP oxalate
A selective 5-HT2A antagonist with almost as high affinity (Ki = 5.3 nM) as ketanserin but with a much lower affinity for 5-HT2C sites (Ki = 620 nM).
カタログ # CAS Number Molecular Formula Unit
sc-203782 N/A C₂₂H₂₆FNO.C₂H₂O₄ 10 mg/50 mg
5-Carboxamidotryptamine maleate
5-HT1 agonist with high affinity at 5-HT1A, 5-HT1B , 5-HT1D, 5-ht5 and 5-HT7 receptors.
カタログ # CAS Number Molecular Formula Unit
sc-203477 74885-09-9 C₁₁H₁₃N₃O ·C₄H₄O₄ 10 mg/50 mg
(5-Hydroxy-1H-indol-3-yl)acetic acid
カタログ # CAS Number Molecular Formula Unit
sc-299847 1321-73-9 C₁₀H₉NO₃ 500 mg
5-Nonyloxytryptamine oxalate
5-HT1B selective agonist, several times more potent than sumatriptan and inactive as a 5-HT1A agonist (Ki at 5-HT1B = 1 nM, selectivity over 5-HT1A > 300-fold).
カタログ # CAS Number Molecular Formula Unit
sc-203480 157798-12-4 C₁₉H₃₀N₂O.C₂H₂O₄ 10 mg/50 mg
8-Hydroxy-DPAT • HBr
Serotonin 5-HT1A agonist.
カタログ # CAS Number Molecular Formula Unit
sc-201129 87394-87-4 C₁₆H₂₅NO•HBr 25 mg/100 mg
8-Hydroxy-PIPAT oxalate
カタログ # CAS Number Molecular Formula Unit
sc-361090 159651-91-9 C₁₆H₂₂INO.C₂H₂O₄ 10 mg/50 mg
(±)α-Methylserotonin maleate
A racemic mixture of α-methylserotonin maleate. Serotonin receptor agonist with preference for 5-HT_A, 5-HT_B, 5-HT_C receptors.
カタログ # CAS Number Molecular Formula Unit
sc-201134 304-52-9 C₁₁H₁₄N₂O.C₄H₄O₄ 10 mg/50 mg
Almotriptan Hydrochloride
A Serotonin 5HT1B /1D-receptor agonist.
カタログ # CAS Number Molecular Formula Unit
sc-210786 154323-46-3 C₁₇H₂₆ClN₃O₂S 10 mg
Altanserin hydrochloride
A selective and potent serotonin 5-HT_2A receptor antagonist. In addition, Altanserin hydrochloride can be used to determine malfunction in serotonergic neurotransmission.
カタログ # CAS Number Molecular Formula Unit
sc-203504 76330-71-7 C₂₂H₂₂FN₃O₂S ·HCl 10 mg/50 mg
Amperozide hydrochloride
カタログ # CAS Number Molecular Formula Unit
sc-203512 75558-90-6 C₂₃H₂₉F₂N₃O.HCl 10 mg/50 mg
Anpirtoline hydrochloride
A serotonin 5-HT1_B receptor agonist (Ki values are 28, 150 and 1490 nM at 5-HT1_B, 5-HT1_A and 5-HT2 receptors respectively).
カタログ # CAS Number Molecular Formula Unit
sc-201108 98330-05-3 C₁₀H₁₃ClN₂S ·HCl 5 mg/25 mg
AS 19
Reported potent 5-HT7 receptor agonist (IC₅₀ = 0.83 nM). Enhances memory consolidation and reverses scopolamine- or dizocilpine-induced amnesia in vivo.
カタログ # CAS Number Molecular Formula Unit
sc-203826 N/A C₁₈H₂₅N₃ 10 mg/50 mg
Asenapine maleate
カタログ # CAS Number Molecular Formula Unit
sc-361110 65576-45-6 C₁₇H₁₆CINO•C₄H₄O₄ 10 mg/50 mg
Azasetron Hydrochloride
A 5-HT3 receptor antagonist which is used as an anti-emetic.
カタログ # CAS Number Molecular Formula Unit
sc-210852 123040-69-7 C₁₇H₂₁Cl₂N₃O₃ 10 mg
BP 554 maleate
Selective 5-HT1A agonist
カタログ # CAS Number Molecular Formula Unit
sc-203851 82900-57-0 C₂₄H₂₈N₂O₇ 10 mg/50 mg
BRL 15572 hydrochloride
A selective h5-HT1D antagonist, displaying 60-fold selectivity over h5-HT1B, with little or no affinity for a range of other receptor types.
カタログ # CAS Number Molecular Formula Unit
sc-202979 193611-72-2 C₂₅H₂₇ClN₂O.HCl 5 mg
BRL 54443
A potent 5-ht_1E/1F receptor agonist.
カタログ # CAS Number Molecular Formula Unit
sc-203855 57477-39-1 C₁₄H₁₈N₂O 10 mg/50 mg
BRL 54443 maleate salt
BRL 54443 maleate salt has been shown to be a potent agonist for the 5-HT1E/1F serotonin receptor.
カタログ # CAS Number Molecular Formula Unit
sc-300302 1197333-54-2 C₁₄H₁₈N₂O•C₄H₄O₄ 10 mg
Bupropion HCl
Shown to produce antagonistic dopamine and norepinephrine depletion. Also shown to inhibit destruction of dopamine neurons in a dose-dependent manner.
カタログ # CAS Number Molecular Formula Unit
sc-201121 31677-93-7 C₁₃H₁₈ClNO ·HCl 50 mg/250 mg
Buspirone hydrochloride
5-HT1A serotonin receptor agonist.
カタログ # CAS Number Molecular Formula Unit
sc-202982 33386-08-2 C₂₁H₃₁N₅O₂ ·HCl 1 g
BW 723C86 hydrochloride
Selective for the HT2B receptor. Anxiolytic and may lead to hyperphagia.
カタログ # CAS Number Molecular Formula Unit
sc-203428 160521-72-2 C₁₆H₁₈N₂OS ·HCl 10 mg/50 mg
CGS 12066B dimaleate
A selective agonist of the serotonin 5-HT_1B receptor. 10-fold selective over the 5-HT_1A receptor and 1000-fold selective over 5-HT_2C receptor.
カタログ # CAS Number Molecular Formula Unit
sc-201106 109028-10-6 C₂₅H₂₅F₃N₄O₈ 10 mg/50 mg
CGS-12066A maleate salt
5-HT1B serotonin receptor agonist.
カタログ # CAS Number Molecular Formula Unit
sc-300345 109028-09-3 C₂₁H₂₁F₃N₄O₄ 25 mg
Cinanserin
Serotonin 5-HT2 antagonist.
カタログ # CAS Number Molecular Formula Unit
sc-201110 1166-34-3 C₂₀H₂₄N₂OS 10 mg
Cinanserin hydrochloride
カタログ # CAS Number Molecular Formula Unit
sc-361149 1166-34-3 (non-salt) C₂₀H₂₄N₂OS.HCl 10 mg/50 mg
cis-Urocanic acid
This 5-HT agonist is a product of uv isomerization of trans-urocanic acid in skin. This leads to immunosuppression via activation of 5-HT2A receptor.
カタログ # CAS Number Molecular Formula Unit
sc-214741 7699-35-6 C₆H₆N₂O₂ 10 mg/50 mg
Cisapride
5-HT4 agonist; stimulates intestinal ACh
カタログ # CAS Number Molecular Formula Unit
sc-203894 81098-60-4 C₂₃H₂₉ClFN₃O₄ 5 mg/50 mg
Citalopram
A selective inhibitor of the 5-hydroxytryptamine transporter (serotonin) and therefore is a potent and selective serotonin reuptake inhibitor.
カタログ # CAS Number Molecular Formula Unit
sc-201123 59729-33-8 C₂₀H₂₁FN₂O 10 mg/50 mg
Citalopram hydrobromide
A selective inhibitor of the 5-hydroxytryptamine transporter (serotonin) and therefore is a potent and selective serotonin reuptake inhibitor.
カタログ # CAS Number Molecular Formula Unit
sc-203551 59729-32-7 C₂₀H₂₁FN₂O.HBr 10 mg/50 mg
Citalopram N-Oxide
A metabolite of Citalopram and a potential selective inhibitor of the 5-hydroxytryptamine transporter (serotonin).
カタログ # CAS Number Molecular Formula Unit
sc-207444 63284-72-0 C₂₀H₂₁FN₂O₂ 1 mg
CJ 033466
5-HT4 partial agonist that is potent and selective. Selectivity for 5-HT4 is substantially greater than that of 5-HT and D2 receptors. Upon oral administration, displays gastro-prokinetic effects. Blocking of hERG is weak.
カタログ # CAS Number Molecular Formula Unit
sc-205257 519148-48-2 C₁₉H₂₈ClN₅O 10 mg/50 mg
Clomipramine hydrochloride
Tricyclic antidepressant. Completely selective serotonin reuptake inhibitor; norepinephrine reuptake inhibitor.
カタログ # CAS Number Molecular Formula Unit
sc-203898 17321-77-6 C₁₉H₂₃ClN₂•HCl 1 g
CP 809101 hydrochloride
Potent and selective 5-HT2C receptor agonist. Displays antipsychotic activity; suppresses condition avoidance responding (CAR) and inhibits PCP and amphetamine-stimulated hyperactivity in rats following subcutaneous administration.
カタログ # CAS Number Molecular Formula Unit
sc-205277 479683-64-2 C₁₅H₁₇N₄OCl ·HCl 10 mg/50 mg
CP 93129 dihydrochloride
Selective 5-HT1B agonist.
カタログ # CAS Number Molecular Formula Unit
sc-203904 127792-75-0 C₁₂H₁₃N₃O•2HCl 10 mg/50 mg
CP 94253 hydrochloride
Potent, selective serotonin 1B (5-HT1B) agonist.
カタログ # CAS Number Molecular Formula Unit
sc-203905 131084-35-0 C₁₅H₁₉N₃O•HCl 10 mg/50 mg
Cyanopindolol hemifumarate
5-HT1A/1B antagonist. Also b-adrenergic antagonist
カタログ # CAS Number Molecular Formula Unit
sc-203906 106469-57-2 C₁₆H₂₁N₃O₂.&frac₁₂;C₄H₄O₄ 10 mg/50 mg
Cyproheptadine hydrochloride
Migraine prophylactic and Non-selective 5HT2 antagonist.
カタログ # CAS Number Molecular Formula Unit
sc-203557 969-33-5 C₂₁H₂₁N ·HCl 50 mg
Demethylchloro Citalopram Hydrochloride
A derivative of Citalopram and a potentially useful internal standard.
カタログ # CAS Number Molecular Formula Unit
sc-207519 64372-52-7 C₁₉H₂₀Cl₂N₂O 1 mg
Dibenzepine HCl
カタログ # CAS Number Molecular Formula Unit
sc-201115 315-80-0 C₁₈H₂₂ClN₃O 100 mg/500 mg
Didemethylchloro Citalopram Hydrochloride
A derivative of Citalopram and potentially useful as an internal standard.
カタログ # CAS Number Molecular Formula Unit
sc-207565 887354-48-5 C₁₈H₁₈Cl₂N₂O 1 mg
Dihydroergocristine mesylate
A semisynthetic ergot alkaloid with enhancing effects on spatial learning and memory acquisition. Demonstrates antagonism at 5-HT (serotonin) receptors and partial agonism/antagonism of dopaminergic and adrenergic receptors.
カタログ # CAS Number Molecular Formula Unit
sc-201117 24730-10-7 C₃₆H₄₅N₅O₈S 200 mg/1 g
Dihydroergotamine Methanesulfonate Salt
A competitive serotonin antagonist and vasoconstrictor.
カタログ # CAS Number Molecular Formula Unit
sc-294343 11032-41-0 C₃₄H₄₁N₅O₈S 10 mg/25 mg
Dolasetron
An antiserotonin used as an antiemetic to prevent nausea and vomiting brought on by chemotherapy or general anaesthesia.
カタログ # CAS Number Molecular Formula Unit
sc-204733 115956-12-2 C₁₉H₂₀N₂O₃ 5 mg/25 mg
Eicosapentaenoyl Serotonin
Eicosapentaenoyl serotonin is a hybrid molecule patterned after arachidonoyl serotonin (sc-201460).
カタログ # CAS Number Molecular Formula Unit
sc-358802 199875-71-3 C₃₀H₄₀N₂O₂ 1 mg/5 mg
Eltoprazine hydrochloride
5-HT₁ and 5-HT_2C receptor partial agonist (K_i values are 40, 52 and 81 nM for 5-HT_1A, 5-HT_1B and 5-HT_2C receptors respectively). Reduces 5-HIAA levels in the striatum and exhibits anti-aggressive behavior in vivo.
カタログ # CAS Number Molecular Formula Unit
sc-203574 98224-03-4 C₁₂H₁₆N₂O₂.HCl 10 mg/50 mg
EMD 386088 hydrochloride
Potent 5-HT6 receptor agonist (EC₅₀= 1.0 nM) that displays selectivity to other 5-HT receptors (IC₅₀ values are 7.4, 110, 180, 240, 450, 620, 660 and 3000 nM for 5-HT6, 5-HT1D, 5-HT1B, 5-HT2A, 5-HT2C, 5-HT4, 5-HT1A and 5-HT7 receptors respectively). Moderate affinity at 5-HT3 receptors (IC₅₀ = 34 nM).
カタログ # CAS Number Molecular Formula Unit
sc-203575 54635-62-0 C₁₄H₁₅N₂Cl•HCl 10 mg/50 mg
ent-Frovatriptan
Serotonin 5-HT1B/1D receptor agonist. It is a triptan drug for the treatment of migraine headaches. Frovatriptan causes vasoconstriction of arteries and veins that supply blood to the head.
カタログ # CAS Number Molecular Formula Unit
sc-207622 158930-18-8 C₁₄H₁₇N₃O 1 mg
Fananserin
Serotonin (5-HT) 2A antagonist. Also Dopamine D4 antagonist. Does not block Dopamine D2.
カタログ # CAS Number Molecular Formula Unit
sc-203951 127625-29-0 C₂₃H₂₄FN₃O₂S•xH₂O 10 mg/50 mg
FLUO-4 (AM)
An intracellular Ca²⁺ indicator that is being replaced by the superior Quest Fluo-8™, AM (sc-361827), which allows for more facile cell loading and has improved spectral properties while keeping the convenient Ex and Em wavelengths.
カタログ # CAS Number Molecular Formula Unit
sc-294596 273221-67-3 C₅₁H₅₀F₂N₂O₂₃ 1 mg
Fluperlapine
Fluperlapine is an atypical antipsychotic agent and ligand for the serotonin receptors 5-HT6/5-HT7.
カタログ # CAS Number Molecular Formula Unit
sc-201119 67121-76-0 C₁₉H₂₀FN₃ 100 mg
Fluvoxamine maleate
A selective serotonin reuptake inhibitor with high affinity for the 5-HT transporter (K_i = 1.6 nM).
カタログ # CAS Number Molecular Formula Unit
sc-203582 61718-82-9 C₁₅H₂₁F₃N₂O₂.C₄H₄O₄ 10 mg/50 mg
GR 113808
カタログ # CAS Number Molecular Formula Unit
sc-361189 144625-51-4 C₁₉H₂₇N₃O₄S 10 mg/50 mg
GR 125487 sulfamate
カタログ # CAS Number Molecular Formula Unit
sc-361190 144625-67-2 C₁₉H₂₆FN₃O₅S.H₂NSO₃H 10 mg/50 mg
GR 127935 hydrochloride
カタログ # CAS Number Molecular Formula Unit
sc-361191 148672-13-3 C₂₉H₃₁N₅O₃.HCl 10 mg/50 mg
GR 127935 hydrochloride hydrate
A selective, potent and orally active 5-HT1B/1D serotonin receptor antagonist.
カタログ # CAS Number Molecular Formula Unit
sc-250068 148642-42-6 (anhydrous) C₂₉H₃₄ClN₅O₄ 10 mg
GR 46611
カタログ # CAS Number Molecular Formula Unit
sc-361195 185259-85-2 C₂₃H₂₇N₃O₂ 10 mg/50 mg
GR 55562 dihydrochloride
カタログ # CAS Number Molecular Formula Unit
sc-361196 172854-55-6 C₂₃H₂₅N₃O₂.2HCl 10 mg/50 mg
Granisetron hydrochloride
5-HT3 antagonist receptor that possesses potent antiemetic activity.
カタログ # CAS Number Molecular Formula Unit
sc-203984 107007-99-8 C₁₈H₂₄N₄O.HCl 10 mg/50 mg
Indatraline hydrochloride
Strong monoamine uptake inhibitor which inhibits transporters for 5-HT (SERT), dopamine (DAT) and noradrenalin (NET) (Ki values are 0.42, 1.7 and 5.8 nM respectively). Centrally active following systemic administration in vivo.
カタログ # CAS Number Molecular Formula Unit
sc-203605 86939-10-8 C₁₆H₁₅Cl₂N.HCl 10 mg/50 mg
Indorenate hydrochloride
5-HT receptor agonist with high affinity for 5-HT1A receptors (pKd = 7.8) and lower affinity for 5-HT1B and 5-HT2C receptors (pKd values are 5.44 and 6.49 respectively). Possesses anti-hypertensive, anorectic, and anxiolytic activity in vivo.
カタログ # CAS Number Molecular Formula Unit
sc-204012 72318-55-9 C₁₃H₁₆N₂O₃ ·HCl 10 mg/50 mg
Ipsapirone
A serotonin-1A agonist that has been found to selectively bind 5-HT1 receptors. Also an anti-apoptotic agent that augments NF-κB, Bcl-XL, catalase, and XIAP expressions in neurons.
カタログ # CAS Number Molecular Formula Unit
sc-203607 95847-70-4 C₁₉H₂₃N₅O₃S 10 mg/50 mg
Isamoltane hemifumarate
5-HT_1B antagonist, approximately 30-fold selective over 5-HT_1A. Does possess affinity for β-adrenergic receptors.
カタログ # CAS Number Molecular Formula Unit
sc-203608 55050-95-8 C₁₆H₂₂N₂O₂•&frac₁₂;C₄H₄O₄ 10 mg/50 mg
Ketanserin tartrate
A seletive serotonin agonist with reported ability to distinguish between various 5-HT subtypes.
カタログ # CAS Number Molecular Formula Unit
sc-201131 83846-83-7 C₂₂H₂₂FN₃O₃··C₄H₆O₆ 50 mg/250 mg
L-694,247
カタログ # CAS Number Molecular Formula Unit
sc-361223 137403-12-4 C₂₀H₂₁N₅O₃S 10 mg/50 mg
Lofepramine
カタログ # CAS Number Molecular Formula Unit
sc-203624 23047-25-8 C₂₆H₂₇ClN₂O 10 mg/50 mg
LP 12 hydrochloride hydrate
This product is a 5-HT7 receptor agonist found to display selectivity over D2, 5-Ht1A and 5-HT2A.
カタログ # CAS Number Molecular Formula Unit
sc-300940 N/A C₃₂H₃₉N₃O··HCl•xH₂O 10 mg
LP 44
High affinity 5-HT7 agonist
カタログ # CAS Number Molecular Formula Unit
sc-224044 824958-12-5 C₂₇H₃₇N₃OS•HCl 10 mg/50 mg
LY 344864 hydrochloride
カタログ # CAS Number Molecular Formula Unit
sc-361245 186544-26-3 C₂₁H₂₂N₃OF.HCl 10 mg/50 mg
LY-310,762 hydrochloride
This product is a selective and potent 5-HT1D serotonin receptor antagonist.
カタログ # CAS Number Molecular Formula Unit
sc-300941 192927-92-7 C₂₄H₂₇O₂N₂F•HCl 5 mg
m-Chlorophenylbiguanide hydrochloride
Prototypical potent and selective 5-HT3 receptor agonist.
カタログ # CAS Number Molecular Formula Unit
sc-203125 2113-05-5 C₈H₁₀CIN₅ ·HCl 100 mg
McN 5652, (+/-)
Potent, orally active 5-HT uptake inhibitor. Inhibits dopamine and noradrenaline uptake in vitro
カタログ # CAS Number Molecular Formula Unit
sc-203627 96795-89-0 C₁₉H₂₁NS 10 mg/50 mg
MDL 11,939
Potent, selective and orally active 5-HT2 receptor antagonist (Ki values are 0.54 and 81.6 nM at 5-HT2A and 5-HT2C receptors respectively).
カタログ # CAS Number Molecular Formula Unit
sc-204069 107703-78-6 C₂₀H₂₅NO 10 mg/50 mg
MDL 72832 hydrochloride
Potent, selective and stereospecific ligand for central and peripheral 5-HT1A recognition sites.
カタログ # CAS Number Molecular Formula Unit
sc-204070 113777-33-6 C₂₂H₃₁ClN₂O₄ 10 mg/50 mg
MDL 73005EF hydrochloride
Potent and selective 5-HT_1A receptor partial agonist with putative anxiolytic properties.
カタログ # CAS Number Molecular Formula Unit
sc-204071 124756-23-6 C₂₀H₂₆N₂O₄.HCl 10 mg/50 mg
MDL-72222
Serotonin 5-HT3 antagonist.
カタログ # CAS Number Molecular Formula Unit
sc-201132 40796-97-2 C₁₅H₁₇Cl₂NO₂ 50 mg
Melperone hydrochloride
Atypical neuroleptic; 5-HT2A/D2 receptor antagonist. Causes an increase in dopamine levels in the medial prefrontal cortex (mPFC) and nucleus accumbens and an increase in ACh release in the medial prefrontal cortex (mPFC). Also binds adrenergic α1 and α2 receptors.
カタログ # CAS Number Molecular Formula Unit
sc-204074 1622-79-3 C₁₆H₂₂FNO•HCl 10 mg/50 mg
Metergoline
Antagonist at 5-HT₁, 5-HT₂, and 5-HT₇ serotonin receptors; also 5-HT_1D ligand. moderate affinity for 5-HT₆ and high affinity for 5-HT₇. Analgesic; antipyretic.
カタログ # CAS Number Molecular Formula Unit
sc-204079 17692-51-2 C₂₅H₂₉N₃O₂ 10 mg/50 mg
Methiothepin maleate
Has moderate affinity for 5-ht5 and high affinity for 5-ht6 and 5-HT7. Also antagonist at 5-HT1 and 5-HT2 Potent 5-HT2 antagonist, also active as 5-HT1 antagonist. Differentiates 5-HT1D sub-types.
カタログ # CAS Number Molecular Formula Unit
sc-203630 20229-30-5 C₂₀H₂₄N₂S₂.C₄H₄O₄ 50 mg
Methylergometrine maleate
Active metabolite of methysergide. Used as an oxytocic.
カタログ # CAS Number Molecular Formula Unit
sc-203631 113-42-8 C₂₀H₂₅N₃O₂ ·C₄H₄O₄ 50 mg/250 mg
Mexiletine hydrochloride
A use dependent blocker of sodium channels in skeletal muscle tissue.
カタログ # CAS Number Molecular Formula Unit
sc-203633 5370-01-4 C₁₁H₁₇NO ·HCl 50 mg
Mianserin hydrochloride
カタログ # CAS Number Molecular Formula Unit
sc-358986 21535-47-7 C₁₈H₂₀N₂ ·HCl 50 mg
Milnacipran hydrochloride
An inhibitor of serotonin and norepinephrine reuptake.
カタログ # CAS Number Molecular Formula Unit
sc-204086 101152-94-7 C₁₅H₂₂N₂O ·HCl 10 mg/50 mg
Mirtazapine
A potent 5-HT2 (pKi 8.05) and 5-HT3 (pKi 8.1) antagonist in addition to being a moderately potent α2 adrenoceptor (pKi 6.9) and histamine H1-antagonist (pKi 9.3).
カタログ # CAS Number Molecular Formula Unit
sc-204088 85650-52-8 C₁₇H₁₉N₃ 10 mg/50 mg
MK 212 hydrochloride
A 5-HT2C serotonin receptor agonist.
カタログ # CAS Number Molecular Formula Unit
sc-203634 64022-27-1 C₈H₁₁CIN₄.HCl 10 mg/50 mg
ML 10302
カタログ # CAS Number Molecular Formula Unit
sc-363330 148868-55-7 C₁₅H₂₁ClN₂O₃ 10 mg
ML 10302 hydrochloride
Potent 5-HT4 partial agonist (EC₅₀ = 4 nM) that displays > 680-fold selectivity over 5-HT3 receptors (Ki values are 1.07 and 730 nM respectively). Increases sAPPα levels in the cortex in an animal model of Alzheimer's disease and exhibits progastrokinetic effects in vivo.
カタログ # CAS Number Molecular Formula Unit
sc-204089 148868-55-7 C₁₅H₂₁CIN₂O₃ ·HCl 10 mg/50 mg
MM 77 dihydrochloride
カタログ # CAS Number Molecular Formula Unit
sc-204090 159311-94-1 C₁₉H₂₇N₃O₃•2HCl•xH₂O 10 mg/50 mg
MMTC
MMTC is endogenous to the rat brain and to human urine. As a result of its antioxidant properties, MMTC may be neuroprotective.
カタログ # CAS Number Molecular Formula Unit
sc-201063 1210-56-6 C₁₃H₁₆N₂O 1 mg/5 mg
Mosapride citrate
Selective serotonin 5-HT4 agonist and 5-HT3 antagonist
カタログ # CAS Number Molecular Formula Unit
sc-203635 112885-42-4 C₂₁H₂₅ClFN₃O₃ ·C₆H₈O₇ 10 mg/50 mg
N-Desmethyl Escitalopram
カタログ # CAS Number Molecular Formula Unit
sc-355637 144025-14-9 C₁₉H₁₉FN₂O··HBr 50 mg
N-Methylquipazine dimaleate
Tertiary amine analog of quipazine that is an agonist at 5-HT3 serotonin receptors with an affinity similar to that of quipazine, but which lacks affinity for central 5-HT1B serotonin receptors.
カタログ # CAS Number Molecular Formula Unit
sc-203639 28614-26-8 C₂₂H₂₅N₃O₈ 20 mg/100 mg
NAN-190
Serotonin 5-HT1A antagonist.
カタログ # CAS Number Molecular Formula Unit
sc-201138 115338-32-4 C₂₃H₂₇N₃O₃··HBr 50 mg/250 mg
Naratriptan Hydrochloride
A triptan drug which is used for the treatment of migraine headaches.
カタログ # CAS Number Molecular Formula Unit
sc-212362 143388-64-1 C₁₇H₂₆ClN₃O₂S 5 mg
NAS-181
Selective r5-HT1B antagonist. Active in vivo Potent, selective antagonist at the rat 5-HT1B receptor (Ki = 47 nM). Increases synthesis and metabolism of 5-HT in the brain following systemic administration and improves passive avoidance retention performance in vivo.
カタログ # CAS Number Molecular Formula Unit
sc-203640 205242-62-2 C₁₉H₂₆N₂O₄.2CH₃SO₃H 10 mg/50 mg
Nefazodone hydrochloride
Serotonin 5-HT2A receptor antagonist and inhibitor of serotonin and noradrenalin uptake.
カタログ # CAS Number Molecular Formula Unit
sc-203156 82752-99-6 C₂₅H₃₂ClN₅O₂•HCl 1 g/5 g
NPEC-caged serotonin
カタログ # CAS Number Molecular Formula Unit
sc-359015 N/A C₁₉H₁₉N₃O₅ 10 mg/50 mg
NPS ALX Compound 4a dihydrochloride
Competitive 5-HT6 antagonist displaying preference over other 5-HT and D2 receptors.
カタログ # CAS Number Molecular Formula Unit
sc-204134 299433-10-6 C₂₅H₂₇Cl₂N₃O₂S 10 mg/50 mg
Olanzapine
A Serotonin (5-HT2) and dopamine (D1/D2) receptor antagonist with anti-cholinergic activity.
カタログ # CAS Number Molecular Formula Unit
sc-212469 132539-06-1 C₁₇H₂₀N₄S 100 mg
Oleamide
Endogenous sleep-inducing lipid. Acts as an agonist at the CB1 cannabinoid receptor (EC50 = 1.64 μM). Also appears to potentiate the actions of 5-HT on 5-HT2A and 2C receptors, and act via an allosteric regulatory site on 5-HT7 receptors.
カタログ # CAS Number Molecular Formula Unit
sc-358696 301-02-0 C₁₈H₃₅NO 10 mg
Olanzapine Lactam Impurity
カタログ # CAS Number Molecular Formula Unit
sc-361832 1017241-34-7 C₁₇H₂₀N₄O₂ 1 mg
Olanzapine Thiolactam Impurity
カタログ # CAS Number Molecular Formula Unit
sc-361833 1017241-36-9 C₁₇H₂₀N₄OS 1 mg
Ondansetron hydrochloride dihydrate
A serotonin-3 (5-HT3) receptor antagonists, used to prevent radiosurgery-induced nausea and vomiting, along with the modulation of alcohol intoxiccation.
カタログ # CAS Number Molecular Formula Unit
sc-205778 99614-01-4 C₁₈H₂₄ClN₃O₃ 100 mg/500 mg
Ondansetron
An antagonist of the serotonin 5-HT₃ receptor. Demonstrates anti-emetic effects.
カタログ # CAS Number Molecular Formula Unit
sc-201127 99614-02-5 C₁₈H₁₉N₃O 10 mg/50 mg
Ondansetron hydrochloride
Selective 5-HT3 antagonist. Antiemetic; preventis emesis induced by cytotoxic drugs and radiation.
カタログ # CAS Number Molecular Formula Unit
sc-204147 103639-04-9 C₁₈H₁₉N₃O.HCl 10 mg/50 mg
Org 12962 HCl
A selective 5-HT2C receptor agonist (pEC50 values are 7.01, 6.38 and 6.28 for 5-HT2C, 5-HT2A and 5-HT2B respectively). Has been shown to display antiaversive effects in a rat model of panic-like anxiety.
カタログ # CAS Number Molecular Formula Unit
sc-301505 210821-63-9 C₁₀H₁₁CIF₃N₃.HCl 10 mg/50 mg
p-MPPF dihydrochloride
This product is a selective 5-HT1A serotonin receptor antagonist. It has been found to be more potent than p-MPPI.
カタログ # CAS Number Molecular Formula Unit
sc-301510 223699-41-0 C₂₅H₂₇FN₄O₂•2HCl 5 mg
Paroxetine maleate
Highly potent and selective 5-HT uptake inhibitor that binds with high affinity to the serotonin transporter (K_i = 0.05 nM).
カタログ # CAS Number Molecular Formula Unit
sc-203658 64006-44-6 C₁₉H₂₀FNO₃•C₄H₄O₄ 10 mg/50 mg
Pizotifen malate
A potent inhibitor of SR-2 receptor activity with potential embryotoxic effects in mice. Also been reported to have acute antagonistic affects on central muscarinic receptors.
カタログ # CAS Number Molecular Formula Unit
sc-201143 5189-11-7 C₁₉H₂₁NS ·C₄H₆O₅ 100 mg/500 mg
PNU 109291
Potent and selective 5-HT1D receptor agonist that displays > 600-fold selectivity over 5-HT1A and 5-HT2A receptors and no activity at 5-HT1B, 5-HT1E, 5-HT2B, 5-HT2C, 5-HT6 and 5-HT7 receptors. Reduces dural plasma extravasation evoked by trigeminal ganglion stimulation.
カタログ # CAS Number Molecular Formula Unit
sc-204203 187665-60-7 C₂₄H₃₁N₃O₃ 10 mg
PNU 142633
Very selective, high affinity 5-HT1D receptor agonist (Ki values are 6 and > 18000 nM at human 5-HT1D and 5-HT1B receptors respectively). Blocks neurogenic plasma protein extravasation and inhibits sympathetically-induced tachycardic responses in vivo.
カタログ # CAS Number Molecular Formula Unit
sc-204204 187665-65-2 C₂₄H₃₀N₄O₃ 10 mg
PNU 22394 hydrochloride
Potent Serotonin 5-HT2C agonist and partial 5-HT2A/5-HT2B agonist. Non-selective between 5-HT2 receptor subtypes. Reduces food intake in rats following subcutaneous administration and displays anorexigenic effects in humans.
カタログ # CAS Number Molecular Formula Unit
sc-204851 15923-78-1 C₁₃H₁₆N₂.HCl 10 mg/50 mg
Quipazine dimaleate
Serotonin 5-HT3 agonist.
カタログ # CAS Number Molecular Formula Unit
sc-201145 4774-24-7 C₂₁H₂₃N₃O₈ 50 mg
R-96544 hydrochloride
Potent, selective 5-HT2 receptor antagonist; displays some selectivity for 5-HT2A receptors (K_i = 1.6 nM). IC₅₀ values are 2.2, 310, 2400, 3700, > 5000 and > 5000 nM for 5-HT2, a1-adrenergic, D2 dopamine, 5-HT1, 5-HT3 and b-adrenergic receptors respectively. Inhibits pressor responses and 5-HT-induced platelet aggregation in vivo.
カタログ # CAS Number Molecular Formula Unit
sc-204223 167144-79-8 C₂₂H₂₉NO₃ ·HCl 10 mg/50 mg
(R)-Citalopram Oxalate
A derivative of Citalopram and a potential selective inhibitor of 5-hydroxytryptamine transporter (serotonin).
カタログ # CAS Number Molecular Formula Unit
sc-219751 219861-53-7 C₂₂H₂₃FN₂O₅ 5 mg
Ramosetron
A serotonin 5HT3 receptor antagonist for the treatment of nausea and vomiting in post-operative cases.
カタログ # CAS Number Molecular Formula Unit
sc-204873 132036-88-5 C₁₇H₁₇N₃O 10 mg/25 mg
Risperidone
Atypical antipsychotic agent that displays 5-HT2A receptor antagonism. Also displays high affinity at D2 receptors (Ki values are 0.4 and 3.13 nM for 5-HT2A and D2 receptors respectively).
カタログ # CAS Number Molecular Formula Unit
sc-204881 106266-06-2 C₂₃H₂₇FN₄O₂ 10 mg/50 mg
Ritanserin
Potent and long-acting 5-HT₂ receptor antagonist (K_i = 0.39 nM). Anxiolytic in vivo.
カタログ # CAS Number Molecular Formula Unit
sc-203681 87051-43-2 C₂₇H₂₅F₂N₃OS 10 mg/50 mg
Ro 04-6790
Potent and selective 5-HT6 receptor antagonist (pKi values are 7.26 and 7.35 at rat and human 5-HT6 receptors respectively). Does not display affinity at a range of other receptors (IC₅₀ > 10 μM). Induces stretching behavior in rats in vivo.
カタログ # CAS Number Molecular Formula Unit
sc-204238 202466-68-0 C₁₂H₁₆N₆O₂S 10 mg/50 mg
Ro 60-0175 fumarate
Potent, selective 5-HT2 receptor agonist; shows selectivity for the 5-HT2C subtype.
カタログ # CAS Number Molecular Formula Unit
sc-204890 169675-09-6 C₁₁H₁₂ClFN₂ ·C₄H₄O₄ 10 mg/50 mg
RS 102221 hydrochloride
カタログ # CAS Number Molecular Formula Unit
sc-361310 185376-97-0 C₂₇H₃₁F₃N₄O₇S.HCl 10 mg/50 mg
RS 127445 hydrochloride
High affinity 5-HT2B receptor antagonist (pKi = 9.5). Displays 1000-fold selectivity for 5-HT2B with good bioavailability.
カタログ # CAS Number Molecular Formula Unit
sc-204244 199864-87-4 C₁₇H₁₆FN₃ ·HCl 10 mg/50 mg
RS 16566 dihydrochloride
カタログ # CAS Number Molecular Formula Unit
sc-361311 175729-69-8 C₁₈H₂₃ClN₄O.2HCl 10 mg/50 mg
RS 23597-190 hydrochloride
Selective and competitive 5-HT4 serotonin receptor antagonist.
カタログ # CAS Number Molecular Formula Unit
sc-203243 149719-06-2 C₁₆H₂₃ClN₂O₃ ·HCl 5 mg
RS 39604 hydrochloride
カタログ # CAS Number Molecular Formula Unit
sc-361313 167710-87-4 C₂₆H₃₆ClN₃O₆S.HCl 10 mg/50 mg
RS 56812 hydrochloride
カタログ # CAS Number Molecular Formula Unit
sc-361315 143137-35-3 C₁₈H₂₁N₃O₂.HCl 10 mg/50 mg
RS 67333 hydrochloride
カタログ # CAS Number Molecular Formula Unit
sc-361316 168986-60-5 C₁₉H₂₉ClN₂O₂.HCl 10 mg/50 mg
RS 67506 hydrochloride
カタログ # CAS Number Molecular Formula Unit
sc-361317 168986-61-6 C₁₈H₂₈ClN₃O₄S.HCl 10 mg/50 mg
RU 24969 hemisuccinate
Potent 5-HT1A/1B and moderate 5-HT2C agonist that may also release 5-HT. Centrally active following systemic administration.
カタログ # CAS Number Molecular Formula Unit
sc-204896 107008-28-6 C₁₄H₁₆N₂O•½C₄H₆O₄ 10 mg/50 mg
S 14506
Highly potent selective 5-HT1A receptor full agonist. Anxiolytic following central administration in vivo.
カタログ # CAS Number Molecular Formula Unit
sc-205497 135721-98-1 C₂₄H₂₇ClFN₃O₂ 10 mg/50 mg
(S)-Citalopram N-Oxide
A derivative of Citalopram and a potential selective inhibitor of the 5-hydroxytryptamine transporter (serotonin).
カタログ # CAS Number Molecular Formula Unit
sc-212881 917482-45-2 C₂₀H₂₁FN₂O₂ 1 mg
(S)-WAY 100135 dihydrochloride
カタログ # CAS Number Molecular Formula Unit
sc-361330 133025-23-7 (free base) C₂₄H₃₃N₃O₂.2HCl 10 mg/50 mg
Sarpogrelate hydrochloride
A selective 5-HT2A receptor antagonist (pKi values are 8.52, 7.43 and 6.57 for 5-HT2A, 5-HT2C and 5-HT2B receptors respectively). Has been shown to display selectivity over 5-HT1, 5-HT3, 5-HT4 H1, H2, M3, α1-adrenergic, α2-adrenergic and β-adrenergic receptors. Also displays cardioprotective activity in vivo.
カタログ # CAS Number Molecular Formula Unit
sc-296371 135159-51-2 C₂₄H₃₁NO₆ ·HCl 10 mg/50 mg
SB 200646 hydrochloride
カタログ # CAS Number Molecular Formula Unit
sc-361332 143797-63-1 C₁₅H₁₄N₄O.HCl 10 mg/50 mg
SB 204741
Potent, selective 5-HT2B antagonist
カタログ # CAS Number Molecular Formula Unit
sc-224279 152239-46-8 C₁₄H₁₄N₄OS 10 mg/50 mg
SB 206553 hydrochloride
カタログ # CAS Number Molecular Formula Unit
sc-361334 158942-04-2 C₁₇H₁₆N₄O.HCl 10 mg/50 mg
SB 216641 hydrochloride
カタログ # CAS Number Molecular Formula Unit
sc-361335 170230-39-4 C₂₈H₃₀N₄O₄.HCl 10 mg/50 mg
SB 221284
Potent, selective 5-HT2C/2B antagonist
カタログ # CAS Number Molecular Formula Unit
sc-224281 196965-14-7 C₁₆H₁₄F₃N₃OS 5 mg
SB 224289 hydrochloride
カタログ # CAS Number Molecular Formula Unit
sc-361336 180083-23-2 C₃₂H₃₂N₄O₃.HCl 10 mg/50 mg/250 mg
SB 228357
カタログ # CAS Number Molecular Formula Unit
sc-361337 181629-93-6 C₂₂H₁₇F₄N₃O₂ 10 mg/50 mg
SB 258585 hydrochloride
カタログ # CAS Number Molecular Formula Unit
sc-361339 209480-63-7 C₁₈H₂₂IN₃O₃S.HCl 10 mg/50 mg
SB 269970 hydrochloride
カタログ # CAS Number Molecular Formula Unit
sc-361342 201038-74-6 C₁₈H₂₈N₂O₃S•HCl 10 mg/50 mg
SB 399885 hydrochloride
Potent, brain penetrant, orally active 5-HT6 antagonist. Displays > 200-fold selectivity for 5-HT6 over other 5-HT receptors (pKi values are 9.11, 8.81 and 9.02 for human recombinant, native rat and native human 5-HT6 receptors respectively).
カタログ # CAS Number Molecular Formula Unit
sc-204264 402713-80-8 C₁₈H₂₁Cl₂N₃O₄S ·HCl 10 mg/50 mg
SB-204070 hydrochloride
A selective 5-HT4 serotonin receptor antagonist.
カタログ # CAS Number Molecular Formula Unit
sc-250965 148702-58-3 C₁₉H₂₇ClN₂O₄•HCl 5 mg
SB-258585 dihydrochloride
5-HT6 serotonin receptor antagonist.
カタログ # CAS Number Molecular Formula Unit
sc-301789 N/A C₁₈H₂₂N₃O₃SI•2HCl 10 mg
SB203186
Potent 5-HT₄ serotonin receptor antagonist.
カタログ # CAS Number Molecular Formula Unit
sc-203257 207572-69-8 C₁₆H₂₀N₂O₂ ·HCl 5 mg
SDZ 205-557 hydrochloride
5-HT3/5-HT4 receptor antagonist.
カタログ # CAS Number Molecular Formula Unit
sc-204273 137196-67-9 C₁₄H₂₂Cl₂N₂O₃ 10 mg/50 mg
SDZ SER 082 fumarate
カタログ # CAS Number Molecular Formula Unit
sc-361356 141474-54-6 C₁₅H₂₀N₂.C₄H₄O₄ 10 mg/50 mg
Serotonin • HCl
A tryptophan amino acid neurotransmitter located in the central nervous system, which functions as an endogenous 5-HT agonist in a variety of biochemical processes.
カタログ # CAS Number Molecular Formula Unit
sc-201146 153-98-0 C₁₀H₁₂N₂O··HCl 100 mg/1 g
Sertraline HCl
An inhibitor of synapsomal serotonin uptake.
カタログ # CAS Number Molecular Formula Unit
sc-201104 79559-97-0 C₁₇H₁₇Cl₂N··HCl 10 mg/50 mg
Spiperone hydrochloride
A 5-HT_2A serotonin and selective D₂-like dopamine receptor antagonist
カタログ # CAS Number Molecular Formula Unit
sc-204293 749-02-0 (anhydrous) C₂₃H₂₆FN₃O₂ ·HCl 50 mg
Spiroxatrine (R 5188)
Serotonin 5-HT1A antagonist.
カタログ # CAS Number Molecular Formula Unit
sc-201148 1054-88-2 C₂₂H₂₅N₃O₃ 10 mg
SR 57227 hydrochloride
Potent, selective 5-HT3 agonist. CNS penetrant and active in vivo.
カタログ # CAS Number Molecular Formula Unit
sc-204301 77145-61-0 C₁₀H₁₅Cl₂N₃ 10 mg/50 mg
Sumatriptan succinate
A selective 5-HT1 receptor agonist with specificity towards 5-HT1D, 5-HT1B and 5-HT1A, which is carried through cells via liposomes.
カタログ # CAS Number Molecular Formula Unit
sc-204314 103628-48-4 C₁₄H₂₁N₃O₂S•C₄H₆O₄ 10 mg/50 mg
Tandospirone hydrochloride
カタログ # CAS Number Molecular Formula Unit
sc-204320 87760-53-0 C₂₁H₃₀ClN₅O₂ 10 mg/50 mg
TCB-2
High affinity 5-HT2_A receptor agonist (K_i values are 0.73 and 0.75 nM for rat and human receptors respectively).
カタログ # CAS Number Molecular Formula Unit
sc-204325 912440-88-1 C₁₁H₁₄BrNO₂ ·HBr 10 mg/50 mg
Tegaserod, Maleate
A gastroproeinetic used in the treatment of irritable bowel syndrome as well as a selective serotonin 5HT4-receptor partial agonist.
カタログ # CAS Number Molecular Formula Unit
sc-212993 189188-57-6 C₂₀H₂₇N₅O₅ 10 mg/50 mg
Tianeptine sodium salt
A selective facilitator of 5-HT uptake in vitro and in vivo with reported inhibition of dopamine uptake.
カタログ # CAS Number Molecular Formula Unit
sc-204345 30123-17-2 C₂₁H₂₄ClN₂NaO₄S 10 mg/50 mg
Trimipramine Maleate Salt
A serotonin transport blocker that also blocks norepinephrine uptake. Categorized as a antidepressant.
カタログ # CAS Number Molecular Formula Unit
sc-213120 521-78-8 C₂₄H₃₀N₂O₄ 1 g
Tropanyl-3,5-dimethylbenzoate
Antagonist of 5-HT3.
カタログ # CAS Number Molecular Formula Unit
sc-204357 N/A C₁₇H₂₃NO₂ 100 mg
Tropisetron hydrochloride
Potent 5-HT3 receptor antagonist; orally active. Selective partial agonist at a7 nicotinic receptors.
カタログ # CAS Number Molecular Formula Unit
sc-204930 105826-92-4 C₁₇H₂₀N₂O₂ ·HCl 10 mg/50 mg
U 92016A
Selective 5-HT1A receptor agonist that displays high intrinsic activity (Ki values are 0.4, 7.7 and 36 nM for 5-HT1A, 5-HT1D and D2 receptors respectively and > 1000 nM for 5-HT2, D1, α1 and α2 receptors). Produces hypotension, hypothermia and 5-HT behavioral syndrome following p.o. administration.
カタログ # CAS Number Molecular Formula Unit
sc-204363 149654-41-1 C₁₉H₂₅N₃ ·HCl 10 mg/50 mg
VER-3323 hemifumarate salt
This product has been shown to be a 5-HT2C/ 5-HT2B serotonin receptor agonist.
カタログ # CAS Number Molecular Formula Unit
sc-301968 N/A C₁₁H₁₅N₂Br•1/2C₄H₄O₄ 50 mg
WAY 161503 hydrochloride
Potent and selective 5-HT2C receptor agonist (K_i= 4 nM; EC₅₀ = 12 nM). Also antidepressant following systemic administration in vivo.
カタログ # CAS Number Molecular Formula Unit
sc-204392 75704-24-4 C₁₁H₁₁Cl₂N₃O•HCl 5 mg/50 mg
WAY 629 hydrochloride
Selective 5-HT2C agonist. K_i values are 56, 2350, 1575 and 815 nM for human recombinant 5-HT2C, 5-HT2A, 5-HT6 and 5-HT7 receptors respectively. Stimulates intracellular Ca²⁺ mobilization in CHO cells expressing human 5-HT2C receptors (EC₅₀ = 72 nM). Reduces food intake in rats.
カタログ # CAS Number Molecular Formula Unit
sc-204393 57756-45-3 C₁₅H₁₈N₂•HCl 10 mg/50 mg
Xaliproden hydrochloride
Orally active, full agonist at 5-HT1A receptors. Increases motoneuron survival and promotes effects of NGF on neurite outgrowth in vitro. Displays neurotrophic activity in several neurodegenerative models in vivo. Binds rat 5-HT1A with high affinity (Ki = 2.0 nM) and is > 300-fold selective over other 5-HT receptor subtypes (IC₅₀ > 650 nM).
カタログ # CAS Number Molecular Formula Unit
sc-203721 90494-79-4 C₂₄N₂₂F₃N ·HCl 10 mg/50 mg
Y-25130 Hydrochloride
Potent and selective serotonin 5-HT3 antagonist.
カタログ # CAS Number Molecular Formula Unit
sc-201150 123040-16-4 C₁₇H₂₀N₃O₃Cl ·HCl 5 mg
Zacopride hydrochloride
Highly potent 5-HT3 receptor antagonist (Ki = 0.38 nM) and 5-HT4 receptor agonist (Ki = 373 nM). Anti-emetic and anxiolytic following systemic administration in vivo.
カタログ # CAS Number Molecular Formula Unit
sc-203723 90182-92-6 C₁₅H₂₀ClN₃O₂•HCl•xH₂O 10 mg/50 mg
Zimelidine dihydrochloride
Selective 5-HT uptake inhibitor; selective over noradrenalin and dopamine uptake (IC₅₀ values are 0.33, 8.2 and 12 μM respectively). Modulates nociception and induces hyperglycemia in vivo, and is an orally active antidepressant.
カタログ # CAS Number Molecular Formula Unit
sc-203725 56775-88-3 C₁₆H₁₇BrN₂ ·2HCl 10 mg/50 mg
Ziprasidone hydrochloride monohydrate
Atypical antipsychotic that displays combined serotonin and dopamine receptor antagonism. Displays high affinity at 5-HT2A receptors with a 5-HT2A/D2 affinity ratio greater than any other clinically available atypical antipsychotics (pKi values are 9.38, 8.88, 8.69, 8.47, 8.32, 8.14, 7.98, 7.49, 7.33 and 6.28 for 5-HT2A, 5-HT2C, 5-HT1D, 5-HT1A, D2, D3, α1, D4, H1 and D1 receptors respectively).
カタログ # CAS Number Molecular Formula Unit
sc-204419 138982-67-9 C₂₁H₂₁ClN₄OS ·HCl ·H₂O 10 mg/50 mg