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Dynactin 1 (H-300) 抗体: sc-11363 |
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- rabbit polyclonal IgG, 200 µg/ml
- epitope corresponding to amino acids 964-1263 of Dynactin 1of human origin
- recommended for detection of p150 and p135 splice variants of Dynactin 1 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including equine, canine, bovine and porcine
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Dynactin 1 Background Information
Dynactin, a multisubunit complex, is a cytoplasmic Dynein-interacting protein that functions as the ”receptor” for the Dynein microtubule motor. Dynactin/ Dynein binding may be required for most, if not all, cytoplasmic Dynein-driven activities and is thought to contribute to the functional diversity of Dynein. Enriched in neurons, Dynactin also binds to microtubules and has been shown to function in diverse processes, including organelle transport, formation of the mitotic spindle and cytokinesis. Dynactin subunits include p22, p50, p62, p150 (also designated Glued) and ARP-1. The p135 splice variant is neuron specific and, unlike p150, does not bind microtubules.
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他の研究者が、Dynactin 1 (H-300): sc-11363抗体およびDynactin 1 (H-300)のconjugate抗体をどのように使用したかを見る。
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Dynactin 1 (H-300)
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Dynactin 1 (H-300): sc-11363. Western blot analysis of Dynactin 1 expression in mouse (A) and rat (B) brain tissue extract.
Dynactin 1 (H-300): sc-11363. Immunofluorescence staining of normal mouse intestine frozen section showing cytoplasmic staining.
Dynactin 1 (H-300): sc-11363. Immunoperoxidase staining of formalin fixed, paraffin-embedded human stomach tissue showing cytoplasmic staining of glandular cells at low (A) and high (B) magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.
Dynactin 1 (H-300): sc-11363. Western blot analysis of Dynactin 1 expression in non-transfected 293: sc-110760 (A), human Dynactin 1 transfected 29T: sc-177152 (B) and HeLa (C) whole cell lysates. Dynactin 1 (H-300): sc-11363. Western blot analysis of Dynactin 1 expression in Ramos whole cell lysate.
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