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HDAC4 抗体(H-92): sc-11418

 |  データシート

(データ分析に基づい)

  • HDAC4 Antibody (H-92) is a rabbit polyclonal IgG provided at 200 µg/ml
  • epitope corresponding to amino acids 530-631 of HDAC4 of human origin
  • recommended for detection of HDAC4 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
  • TransCruz reagent for ChIP application, sc-11418 X, 200 µg/0.1 ml
  • See 35 citations for HDAC4 抗体 (H-92)
 
免疫原による全長%抗体%タンパク質配列は、以下をハイライトしました。
MSSQSHPDGLSGRDQPVELLNPARVNHMPSTVDVATALPLQVAPSAVPMDLRLDHQFSLPVAEPALREQQLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHIKQQQEMLAMKHQQELLEHQRKLERHRQEQELEKQHREQKLQQLKNKEKGKESAVASTEVKMKLQEFVLNKKKALAHRNLNHCISSDPRYWYGKTQHSSLDQSSPPQSGVSTSYNHPVLGMYDAKDDFPLRKTASEPNLKLRSRLKQKVAERRSSPLLRRKDGPVVTALKKRPLDVTDSACSSAPGSGPSSPNNSSGSVSAENGIAPAVPSIPAETSLAHRLVAREGSAAPLPLYTSPSLPNITLGLPATGPSAGTAGQQDTERLTLPALQQRLSLFPGTHLTPYLSTSPLERDGGAAHSPLLQHMVLLEQPPAQAPLVTGLGALPLHAQSLVGADRVSPSIHKLRQHRPLGRTQSAPLPQNAQALQHLVIQQQHQQFLEKHKQQFQQQQLQMNKIIPKPSEPARQPESHPEETEEELREHQALLDEPYLDRLPGQKEAHAQAGVQVKQEPIESDEEEAEPPREVEPGQRQPSEQELLFRQQALLLEQQRIHQLRNYQASMEAAGIPVSFGGHRPLSRAQSSPASATFPVSVQEPPTKPRFTTGLVYDTLMLKHQCTCGSSSSHPEHAGRIQSIWSRLQETGLRGKCECIRGRKATLEELQTVHSEAHTLLYGTNPLNRQKLDSKKLLGSLASVFVRLPCGGVGVDSDTIWNEVHSAGAARLAVGCVVELVFKVATGELKNGFAVVRPPGHHAEESTPMGFCYFNSVAVAAKLLQQRLSVSKILIVDWDVHHGNGTQQAFYSDPSVLYMSLHRYDDGNFFPGSGAPDEVGTGPGVGFNVNMAFTGGLDPPMGDAEYLAAFRTVVMPIASEFAPDVVLVSSGFDAVEGHPTPLGGYNLSARCFGYLTKQLMGLAGGRIVLALEGGHDLTAICDASEACVSALLGNELDPLPEKVLQQRPNANAVRSMEKVMEIHSKYWRCLQRTTSTAGRSLIEAQTCENEEAETVTAMASLSVGVKPAEKRPDEEPMEEEPPL

追加情報をチェックHDAC Antibodiesを含めてHDAC, HDAC1, HDAC2, HDAC3, HDAC4, HDAC5, HDAC6, HDAC7, HDAC8, HDAC9, HDAC10HDAC11.

も見るchemical HDAC4 Inhibitors for functional analysis of cellular responses to HDAC4.


注文情報参考文献Gene情報
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WB   IP   IF   IHC(P)   ChIP   siRNA  
Set Currency

 注文情報
製品名カタログ #Unit価格数量追加お気に入り
HDAC4 Antibody (H-92) sc-11418 200 µg/ml $279
HDAC4 Antibody (H-92) X sc-11418 X 200 µg/0.1 ml $279
 CRISPR/ Cas9 KO と HDRプラスミド 詳細は、製品名をクリックしてください。
製品名カタログ #Unit価格数量追加お気に入り
HDAC4 CRISPR/Cas9 KO Plasmid (m) sc-431586 20 µg $345
HDAC4 HDR Plasmid (m) sc-431586-HDR 20 µg $385
HDAC4 CRISPR/Cas9 KO Plasmid (h) sc-400388 20 µg $345
HDAC4 HDR Plasmid (h) sc-400388-HDR 20 µg $385
 siRNA 遺伝子サイレンサー 詳細は、製品名をクリックしてください。
製品名カタログ #Unit価格数量追加お気に入り
HDAC4 siRNA (h) sc-35540 10 µM $258
HDAC4 siRNA (m) sc-35541 10 µM $258
HDAC4 (h)-PR sc-35540-PR 10 µM, 20 µl $23
HDAC4 (m)-PR sc-35541-PR 10 µM, 20 µl $23
 shRNAプラスミド 詳細は、製品名をクリックしてください。
製品名カタログ #Unit価格数量追加お気に入り
HDAC4 shRNA Plasmid (h) sc-35540-SH 20 µg $520
HDAC4 shRNA Plasmid (m) sc-35541-SH 20 µg $520
 shRNA レンチウイルス粒子 詳細は、製品名をクリックしてください。
製品名カタログ #Unit価格数量追加お気に入り
HDAC4 shRNA (h) Lentiviral Particles sc-35540-V 200 µl $625
HDAC4 shRNA (m) Lentiviral Particles sc-35541-V 200 µl $625
 WB用ポジティブコントロール細胞溶解物 詳細は、製品名をクリックしてください。
製品名カタログ #Unit価格数量追加お気に入り
HDAC4 (h): 293T Lysate sc-115502 100 µg/200 µl $205
HeLa Whole Cell Lysate sc-2200 500 µg/200 µl $104
Jurkat Whole Cell Lysate sc-2204 500 µg/200 µl $104
HeLa nuclear extract sc-2120 250 µg/0.05 ml $143
Jurkat nuclear extract sc-2132 250 µg/0.05 ml $143
KNRK nuclear extract sc-2141 250 µg/0.05 ml $143
NIH/3T3 nuclear extract sc-2138 250 µg/0.05 ml $143
NIH/3T3 Whole Cell Lysate sc-2210 500 µg/200 µl $104
 
動物種 遺伝子名 Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
ヒト HDAC4 9759 2q37.3 NM_006037, XM_001126419 P56524
605314
マウス Hdac4 208727 1 D Q6NZM9
N/A
 


In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones (1). Acetylation of lysine residues in the amino terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA (1,2). Conversely, the deacetylation of histones is associated with transcriptional silencing (3). Several mammalian proteins have been identified as nuclear histone acetylases, including GCN5, p300/CBP, PCAF (p300/CBPassociated factor), HAT1, and the TFIID subunit TAF II p250 (4,5). Mammalian HDAC1 (also designated HD1), HDAC2 (also designated RPD3) and HDAC3-6, have been identified as histone deacetylases (6-9).

HDAC4 Antibody (H-92) 参考文献
他の研究者のHDAC4 Antibody (H-92)またはHDAC4 Antibody (H-92)標識を使用した方法をご覧下さい。


35 合計引用文献数
引用文献をロード中。
 
HDAC4 Antibody (H-92) Data
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HDAC4 (H-92): sc-11418. Immunofluorescence staining of methanol-fixed HeLa cells showing nuclear and cytoplasmic localization.
HDAC4 (H-92): sc-11418. Western blot analysis of HDAC4 expression in NIH/3T3 (A) and Jurkat (B) whole cell lysates and HeLa (C), KNRK (D) and NIH/3T3 (E) nuclear extracts.
HDAC4 (H-92): sc-11418. Western blot analysis of HDAC4 expression in non-transfected: sc-117752 (A) and human HDAC4 transfected: sc-115502 (B) 293T whole cell lysates.
HDAC4 (H-92): sc-11418. Immunoperoxidase staining of formalin fixed, paraffin-embedded human pancreas tissue showing cytoplasmic staining of glandular cells.
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