UBL4A (C-24) 抗体: sc-130285

UBL4A Background Information
The distal portion of the long arm of the human X chromosome is one of the most gene dense portions in the entire human genome and also contains many genes that have been linked to genetic diseases. The gene encoding the 157 amino acid protein, UBL4A (Ubiquitin-like protein 4A), has a CpG island in the 5' region and is located on the X chromosome in close proximity to the gene encoding G6PD. UBL4A, also known as GDX, has been characterized as a ubiquitously expressed and highly conserved protein from humans to plants. The N-terminal region of UBL4A shares 43% sequence identity with ubiquitin, however the C-terminal region has no homology to ubiquitin and it is therefore unlikely that UBL4A plays any role in targeting cellular proteins for degradation. Due to gene promoter features, such as being rich in G-C residues, lacking TATA boxes and the repetition of the Sp1 transcription factor binding site, it is likely that the gene encoding UBL4A functions as a housekeeping gene.