epitope mapping near the N-terminus of eIF4A of Saccharomyces cerevisiae origin
recommended for detection of eIF4A of yeast origin and eIF4AI, eIF4AII and eIF4AIII of human and, to a lesser extent, mouse and rat origin by WB, IP and ELISA
eIF4A Background Information mRNA translation in eukaryotic cells involves a set of proteins termed translation initiation factors (eIFs), several of which are involved in the binding of ribosomes to mRNA. These include eIF4G, a modular scaffolding protein, and eIF4A, an RNA helicase, of which two closely related forms are known in mammals. eIF4A, in conjunction with eIF4B, catalyzes the ATP-dependent melting of RNA secondary structure in the 5'-untranslated region of mRNA during translation initiation.Th interaction of eIF4A and eIF4G is required for translation and cell growth.
eIF4A (yN-20)
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eIF4A (yN-20): sc-27227. Western blot analysis of eIF4A expression in HeLa whole cell lysate.
eIF4AI (yN-20): sc-27227. Western blot analysis of eIF4A expression in K-562 whole cell lysate.
