epitope mapping near the C-terminus of Glutathione S-transferase Theta 1 of human origin
recommended for detection of GSTT1 of mouse, rat and human origin and, to a lesser extent, GSTT3 of mouse origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine and bovine
GSTT1 Background Information The GST superfamily is made up of several subfamilies. Glutathione S-transferase P (GSTP1) belongs to the Pi subfamily and is involved in the conjugation of reduced glutathione to a variety of endogenous and exogenous hydrophobic electrophiles. Glutathione S-transferase Mu 1 (GSTM1) is a cytoplasmic liver protein belonging to the Mu family and has the same basic functions as GSTP1-1. Glutathione S-transferase theta 1 (GSTT1), a cytoplasmic homodimer belonging to the Theta family, is expressed in erythrocytes. It is active in the reduced glutathione conjugation and also displays glutathione peroxidase activity with cumene hydroperoxide.
GSTT1 (E-17)
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GSTT1 (E-17): sc-28498. Western blot analysis of GSTT1 expression in Hep G2 whole cell lysate.
