TAF I p110 Background Information For gene transcription governed by RNA polymerase I, the human transcription factor SL1 (mouse TIF-IB) directs the assembly of initiation complexes at the prompter. Like TFIID, which directs transcription by RNA polymerase II, SL1/TIF-IB contains the TATA-binding protein (TBP) and a set of TBP-associated factors (TAFs). The three TAF I subunits, hTAF I p110, hTAF I p63 and hTAF p48 (or mouse TAF I p95, TAF I p68 and TAF I p48) are all integral components of SL1/TIF-IB. The mutually exclusive binding of either TAF I or TAF II subunits to TBP is believed to direct the formation of promoter- and RNA polymerase-specific complexes.
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TAF I p110 (C-18)
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TAF I 110 (C-18): sc-6566. Western blot analysis of TAF I p110 expression in PC-3 nuclear extract.
TAF I p110 (C-18): sc-6566. Western blot analysis of TAF I p110 expression in non-transfected: sc-117752 (A) and truncated human TAF I p110 transfected: sc-114680 (B) 293T whole cell lysates.
