Ebi2 Background Information Epstein-Barr virus-induced gene 2 (Ebi2) is a 357 amino acid multi pass membrane protein. It is expressed in B-lymphocytes and lymphoid tissues and may function in the modulation of the immune system. Out of the nine genes that are induced by the Epstein-Barr virus, Ebi2 exhibits the highest levels of up-regulation. Ebi2 is a G-protein coupled receptor that signals through the G-protein Gåi. Ebi2 contains seven hydrophobic transmembrane regions and a putative N-linked glycosylation site at its extracellular N-terminus. Ebi2 is believed to be involved in regulating the effects of the Epstein-Barr virus on B-lymphocytes. In addition, Ebi2 may play a role mediating normal lymphocyte functions.
Ebi2 (N-20)
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EBI2 (N-20): sc-66439. Western blot analysis of EBI2 expression in Raji (A), U266 (B), U-698-M (C), NAMALWA (D) and Ramos (E) whole cell lysates.
Ebi2 (N-20): sc-66439. Immunoperoxidase staining of formalin fixed, paraffin-embedded human stomach tissue showing cytoplasmic staining of glandular cells at high magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.
